To make room in the hand for more useful cards, low-value cards that do not fit into any possible runs or sets should be discarded as soon as possible. Discarding partrammy novelicular cards can also be a calculated tactic to trick opponents into thinking that you are trying to form different sets or runs. You can confuse your opponents' calculations and obtain an advantage in the game by discarding a card that does not fit into your current plan. However, it's also crucial to know which cards to hold onto.